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AD 1500
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Treaty of Granada gives Naples to France and Sicily to Aragon
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AD 1502
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War breaks out between the French and Spanish over Naples
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AD 1516
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Montenegro placed under the suzerainty of the Ottoman Empire
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AD 1519
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Charles I of Spain becomes Holy Roman Emperor, Charles V
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AD 1520
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Christian II of Denmark and Norway defeats Swedes at Lake Åsunde and becomes king of Sweden
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AD 1520
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Alliance formed between England and France at Field of the Cloth of Gold
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AD 1521
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Suleiman I, Ottoman Sultan, conquers Belgrade and invades Hungary
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AD 1526
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Battle of Mohacs; Suleiman I defeats Louis II of Hungary
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AD 1529
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Peace of Cambrai: Francis I of France renounces rights in Italy, Flanders and Artois; Charles V renounces claims to Burgundy
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AD 1534
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Francis I signs the Treaty of Augsburg, an alliance with the Protestant princes against Charles V
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AD 1537
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Alliance of French and Ottomans attack Charles V's forces in the Mediterranean
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AD 1541
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Hungary becomes an Ottoman province
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AD 1542
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Pope Paul III establishes the Roman Inquisition
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AD 1543
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Francis I of France attacks Charles V in Netherlands and northern Spain
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AD 1544
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Treaty of Crépy: Francis I promises emperor Charles V his support against the Protestants
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AD 1549
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Renewed war between England and France
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AD 1551
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Henry II of France resumes the war against emperor Charles V
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AD 1552
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Battle of Szegedin: Turks invade Hungary again
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AD 1555
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Emperor Charles V signs Peace of Augsburg
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AD 1556
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Charles V gives up title of Holy Roman Emperor and king of Spain; his brother Ferdinand becomes Holy Roman Emperor and Habsburg family divides into Austrian and Spanish branches
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AD 1556
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Spain takes control of the Flanders region
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AD 1558
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Turks capture Balearic Islands from Spain and raid the mainland
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AD 1563
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Ottomans invade Malta
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AD 1566
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Beginning of war between Spain and Protestant United Provinces in northern Netherlands and their ally England
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AD 1571
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Ottomans lose naval battle of Lepanto to a group of western allies and their sea-power declines
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AD 1576
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Spain captures Antwerp
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AD 1577
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Samos falls to Turks
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AD 1579
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Union of Utrecht: unites southern Netherlands under Duke of Parma, governor in the name of Felipe II of Spain
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AD 1581
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Oath of Abjuration: United Provinces proclaim independence from Spain
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AD 1585
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England sends troops to aid Netherlands rebellion against Spanish rule; beginning of Anglo-Spanish War
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AD 1593
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Ottomans begin campaign against Habsburgs; start of the Fifteen Years' War
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AD 1594
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Serbs rebel against Ottoman rule
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AD 1595
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France declares war on Spain
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AD 1595
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Battle of Guirgevo; Transylvania defeats Ottomans and secures control of Wallachia
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AD 1595
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Bulgaria rebels against Ottoman rule
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AD 1601
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War between France and Savoy ends with French victory at Chambéry
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AD 1606
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Treaty of Zsitvatorok ends Fifteen Years' War between the Habsburgs and the Ottoman Empire
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AD 1607
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Battle of Gibraltar: Dutch fleet destroy anchored Spanish fleet
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AD 1609
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The Netherlands and Spain agree to the Twelve Years' Truce in the Eighty Years' War
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AD 1611
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War between Denmark and Sweden over control of the Baltic
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AD 1613
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Ottomans invade Hungary
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AD 1618
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Bohemian revolt against Habsburg authority starts Thirty Years' War
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AD 1621
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Spain's truce with the Protestant northern Netherlands ends and war resumes
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AD 1624
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Alliance of France, Holland, England, Sweden, Denmark, Savoy and Venice against Habsburg
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AD 1635
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Louis XIII of France declares war on Spain
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AD 1636
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Open war between France and Holy Roman Empire
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AD 1640
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Wars in Portugal and Catalunya
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AD 1640
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Portugal gains independence from Spain
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AD 1643
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Sweden invades Denmark
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AD 1644
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Habsburg defeated by French, Swedish and Dutch
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AD 1648
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Peace of Westphalia; ends Thirty Years' War
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