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AD 1254
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Death of Conrad IV; Conradin becomes Holy Roman Emperor
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AD 1259
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Treaty of Paris: Louis IX cedes territory to Henry III of England, who gives up all claims to the Plantagenet fiefs
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AD 1263
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Charles of Anjou seizes Sicily
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AD 1273
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Rudolf of Habsburg elected Holy Roman Emperor
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AD 1281
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Pope Martin IV and Venice support Charles of Anjou against the Byzantine empire
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AD 1282
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Pedro III of Aragon seizes Sicily
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AD 1302
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Macedonia and Greece partly ravaged by Catalan mercenaries
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AD 1309
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Papal residence at Avignon begins
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AD 1312
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Henry VII crowned Holy Roman Emperor at Rome
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AD 1324
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Outbreak of warfare between France and England in Gascony
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AD 1326
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Aragón captures Sardinia from the Genoese
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AD 1328
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Louis crowned Holy Roman Emperor in Rome, Pope John XXII declares a crusade against him
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AD 1337
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Edward III claims kingdom of France; Start of Hundred Years' War
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AD 1354
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Ottoman-Turkish armies occupy the Byzantine fortress of Gallipoli and begin expansion into the Balkans
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AD 1360
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Formation of Hanseatic League
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AD 1360
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Treaty of Brétigny ends first phase of Hundred Years' War
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AD 1361
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War between Hanseatic League and Denmark
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AD 1369
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Charles V renounces treaty of Brétigny: war is declared
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AD 1370
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Peace of Stralsund ends war between the Denmark and Hanseatic league
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AD 1371
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Ottomans defeat the Serbs on the River Maritsa
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AD 1378
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Beginning of the Great Schism as two popes are elected, Urban VI in Rome and Clement VII who eventually returned to Avignon
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AD 1378
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Renewal of Hundred Years' War
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AD 1380
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Ottomans occupy Macedonia
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AD 1388
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Bulgaria becomes a tributary state of the Ottomans
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AD 1389
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Mongol 'Golden Horde' recaptures Moscow
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AD 1389
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Battle of Kosovo: Serbian Empire falls to Ottoman Turks
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AD 1396
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Treaty of Leulinghen ends second phase of Hundred Years' War
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AD 1396
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Ottoman rule established over much of Anatolia
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AD 1397
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Union of Kalmar unites Denmark, Sweden, and Norway under one monarch
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AD 1397
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Ottomans Turks capture Athens and besiege Constantinople
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AD 1399
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Mongol victory over Lithuanians at River Varskala, Ukraine
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AD 1400
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Ottomans control much of the Balkans
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AD 1409
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Opening of the Council of Pisa, which deposes both popes (who refuse to accept the decision) and elects a third, Alexander V
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AD 1417
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The Council of Constance elects Pope Martin V: end of the Great Schism
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AD 1431
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Henry VI of England crowned king of France
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AD 1443
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Alfonso V of Aragon and Sicily takes Naples, expelling King Rene of Anjou
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AD 1448
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Ottomans under Murad II win decisive victory over Hungary at Kosovo
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AD 1450
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Norway accepts Act of Union with Denmark
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AD 1453
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Fall of Bordeaux to France ends Hundred Years' War: England loses all territory in France except Calais
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AD 1453
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Ottomans take Constantinople; Byzantium comes under Islamic control
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AD 1454
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Beginning of Thirteen Years' War between Poland and Teutonic order
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AD 1456
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Hungarians defeat Ottomans at Battle of Belgrade
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AD 1457
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Christian of Denmark and Norway crowned king of Sweden
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AD 1458
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The French occupy Genoa; Alfonso V dies and is succeeded by Ferrante in Naples and John II in Sicily and Aragon
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AD 1459
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Serbia falls to Ottoman Empire
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AD 1460
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Turks capture Mistra, Greece
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AD 1482
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Treaty of Arras: Burgundy and Picardy are absorbed into France
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AD 1482
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Ottomans conquer Bosnia and Herzegovina
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AD 1490
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Anglo-Spanish alliance against France supported by Maximillian I of Austria
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AD 1494
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Death of Ferrante of Naples; Charles VIII of France claims the kingdom and invades Italy: start of 'Italian Wars'
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AD 1495
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Venice, Milan, Spain, the pope, and the emperor set up a Holy League against Charles VIII of France after he seizes Naples
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AD 1496
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Emperor Maximilian I enters Italy to remove the remaining French
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AD 1497
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King John of Denmark invades Sweden and reunites Norway, Sweden and Denmark
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AD 1499
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Second Turko-Venetian war
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