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332 BC
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Alexander the Great takes Egypt from the Persians
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331 BC
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Alexander founds Alexandria and leaves Egypt
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331 BC
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Cleomenes of Naucratis is appointed governor of Egypt
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323 BC
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Alexander dies from a fever in Babylon leaving a huge empire and a succession crisis
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323 BC
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Perdiccas, one of Alexander's generals and regent of the empire, appoints Ptolemy as satrap of Egypt
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307 BC
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Ptolemy I creates the library of Alexandria (Museum)
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306 BC
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Antigonus makes a failed attempt to invade Egypt
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306 BC
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Ptolemy I declares himself king of Egypt and takes the title Pharaoh.
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300 BC
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Ptolemy I builds the Pharos of Alexandria
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288 BC
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Ptolemy I makes his younger son, Ptolemy Philadelphus, co-regent
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281 BC
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Ptolemy II Philadelphus becomes ruler of Egypt
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274 BC
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Magus of Cyrene attempts to gain independence from Ptolemaic rule
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274 BC
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Antiochus I attempts to take Ptolemaic lands; start of the First Syrian War
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271 BC
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Ptolemy II regains lands lost to Antiochus; end of the First Syrian War
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271 BC
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Cyrenaica declares its independence from Ptolemaic rule
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260 BC
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Antiochus II attacks Ptolemaic lands in Asia; start of the Second Syrian War
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258 BC
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Battle of Cos; Antiochus II defeats Ptolemy II in a naval battle
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253 BC
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Antiochus II marries daughter of Ptolemy II; end of Second Syrian War
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250 BC
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Cyrenaica brought back under Ptolemaic rule
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246 BC
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Ptolemy II declares war on the Seleucids; start of the Third Syrian War
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246 BC
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Ptolemy III Euergetes becomes ruler of Egypt
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241 BC
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Peace treaty ends Third Syrian War
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221 BC
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Ptolemy IV Philopator becomes ruler of Egypt
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219 BC
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Antiochus III launches attack on Egypt; start of Fourth Syrian War
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217 BC
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Peasants revolt due to increasingly high taxes.
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217 BC
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Battle of Raphia; Ptolemy IV defeats Antiochus III; end of the Fourth Syrian War
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204 BC
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Death of Ptolemy IV provokes succession crisis; Ptolemy V is still a child
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202 BC
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Antiochus III attempts to take Ptolemaic lands; start of the Fifth Syrian War
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200 BC
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Rome, concerned about potential grain shortages, gets assurances from Antiochus that he will not invade Egypt itself
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198 BC
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Antiochus III takes Palestine
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196 BC
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Ptolemy V crowned; this occasion commemorated by the Rosetta Stone
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195 BC
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Peace treaty ends the Fifth Syrian War
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180 BC
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Ptolemy VI Philometor becomes ruler of Egypt
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170 BC
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Ptolemy VIII Euergetes II becomes ruler of Egypt
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131 BC
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Cleopatra II Philometora Soteira becomes opposing ruler
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116 BC
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Ptolemy IX Soter II becomes co-ruler of Egypt with his mother Cleopatra III
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107 BC
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Ptolemy X Alexander becomes ruler of Egypt
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80 BC
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Ptolemy XII Neos Dionysos becomes ruler of Egypt
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51 BC
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Cleopatra VII Thea Neotera becomes co-ruler of Egypt with Ptolemy XIII (until 47 BC), then Ptolemy XIV (until 44 BC) and then Ptolemy XV Caesarion (until 30 BC)
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48 BC
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Roman general Pompey flees to Egypt during the Roman Civil War, but is beheaded by Ptolemy XIII
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48 BC
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Julius Caesar, angered by Pompey's murder, takes Alexandria
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47 BC
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Caesar besieged in Alexandria by Egyptian forces.
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47 BC
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Caesar deposes Ptolemy XIII and puts Cleopatra VII on throne of Egypt
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44 BC
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Cleopatra murders Ptolemy XIV.
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42 BC
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Mark Antony fathers two of Cleopatra's children
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37 BC
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Mark Antony returns to Alexandria permanently
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31 BC
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Octavian (later Augustus) persuades Rome to declare war on Egypt
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31 BC
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Battle of Actium; Rome defeats Cleopatra and Mark Antony
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30 BC
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Despite winning a victory at Alexandria, Antony's troops desert him
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30 BC
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Antony and Cleopatra commit suicide and Egypt comes under Roman control
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